ISSN 1662-4009 (online)

ey0015.1-9 | New clinical investigation | ESPEYB15

1.9 Divergent responses to kisspeptin in children with delayed puberty

YM Chan , MF Lippincott , TO Kusa , SB Seminara

To read the full abstract: JCI Insight 2018;3. pii: 99109The effects of kisspeptin administration in adults are well known. Whatever, the mode of administration, kisspeptin elicits an increase of LH and FSH blood levels in normal men and women. By analogy to rodents and non-human primates, it has been speculated that the response to kisspeptin is majorated at puberty in humans, which could be...

ey0017.7-4 | Clinical Guidance | ESPEYB17

7.4. Using kisspeptin to predict pubertal outcomes for youth with pubertal delay

YM Chan , MF Lippincott , P Sales Barroso , C Alleyn , J Brodsky , H Granados , SA Roberts , C Sandler , A Srivatsa , SB Seminara

To read the full abstract: Journal of clinical endocrinology and metabolism vol. 105,8 (2020): dgaa162. doi: https://academic.oup.com/jcem/article/105/8/dgaa162/5813981This longitudinal study (n =16) suggests that responses to kisspeptin administration could predict later pubertal outcomes for patients with delayed puberty. The management of...